Multifunctionality of statins as antimicrobials
نویسندگان
چکیده
The potential of statins as antimicrobials has been recognized for more than a decade; unfortunately, minimal progress in exploring this promise. This mini review highlights the structure and their relevance antimicrobial co-drug. current information on inhibition mechanism bacterial, fungal, viral, biofilms is also described.
منابع مشابه
View of statins as antimicrobials in cardiovascular risk modification.
Atherosclerosis is a complex arterial pathological development underlying heart attack and stroke and a leading cause of death in developed and now also in developing countries. The primary processes that lead to the inflammatory lipid-laden proliferative lesion, obstructing the blood flow, and referred to as atherosclerotic plaque are dyslipidaemia and inflammation. Here, we will review one of...
متن کاملEndolysins as antimicrobials.
Peptidoglycan (PG) is the major structural component of the bacterial cell wall. Bacteria have autolytic PG hydrolases that allow the cell to grow and divide. A well-studied group of PG hydrolase enzymes are the bacteriophage endolysins. Endolysins are PG-degrading proteins that allow the phage to escape from the bacterial cell during the phage lytic cycle. The endolysins, when purified and exp...
متن کاملMetallic Nanoparticles as Alternative Antimicrobials
Submit Manuscript | http://medcraveonline.com treating these and other bacterial infections currently exist; there is still an essential need for new and improved approaches for bacterial destruction. Nanomedicine is one approach to overcome challenges of conventional drug delivery systems based on the development and fabrication of nanostructures. Various types of nanoparticulate systems have ...
متن کاملStatins as antithrombotic drugs.
Statins as Antithrombotic Drugs Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2013 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/CIRCULATIONAHA.112.145334 2013;127:251-257 Circulation. http://circ.ahajournals.org/content/127/2/251 World Wide Web at: The online ve...
متن کاملStatins as immunomodulatory agents.
Statins have long been thought to exert their benefits by reducing cholesterol synthesis. However, the fact that mevalonate is the precursor of isoprenoids that regulate diverse cellular functions has led investigators to examine pleiotropic effects for these agents. Major histocompatibility complex class II (MHC-II) molecules, which affect the immune response and organ rejection after transpla...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: World Journal of Biology Pharmacy and Health Sciences
سال: 2022
ISSN: ['2582-5542']
DOI: https://doi.org/10.30574/wjbphs.2022.11.3.0114